IVF Medication Guide
Understand your IVF medication protocol including dosing, timing, and side effects
Last updated: December 2024
Medication Storage Guide
Refrigerate (2-8°C):
Gonal-F, Follistim, Ovidrel, Growth Hormone
Room Temperature:
Menopur, Cetrotide, Ganirelix, Lupron (after first use)
Special Instructions:
Menopur needs mixing, Progesterone in oil may need warming
Protocol Comparison
Antagonist Protocol
Duration: ~10-12 days • Best for: Most patients, PCOS • Lower OHSS risk
Long Lupron Protocol
Duration: ~4-6 weeks • Best for: Normal responders • More control
Flare Protocol
Duration: ~10-12 days • Best for: Poor responders • Maximum stimulation
Common Questions
How painful are IVF injections?
Most IVF injections use very thin needles similar to insulin injections. Subcutaneous injections (like Gonal-F, Follistim) cause minimal discomfort. Intramuscular progesterone injections are more uncomfortable but manageable. Your clinic will provide training and tips to minimize discomfort, such as icing the area beforehand and rotating injection sites.
What if I miss a medication dose?
Contact your clinic immediately if you miss a dose. Timing is critical for IVF medications, especially trigger shots. For stimulation medications, your clinic may adjust your next dose or extend your monitoring. Never double up on doses without specific instructions from your doctor.
How should I store IVF medications?
Most gonadotropins (Gonal-F, Follistim) require refrigeration at 2-8°C before first use. Some can be stored at room temperature after opening. Menopur, Cetrotide, and Ganirelix are typically room temperature stable. Always check individual medication instructions and keep medications away from light and heat.
What are the most common side effects?
Common side effects include bloating, mild cramping, headaches, mood swings, breast tenderness, and injection site reactions. More serious but rare complications include ovarian hyperstimulation syndrome (OHSS). Contact your clinic immediately if you experience severe abdominal pain, rapid weight gain, difficulty breathing, or decreased urination.